Tirzepatide works uniquely by activating two key receptors in the body—GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). This dual action helps regulate blood sugar levels while also reducing appetite and promoting weight loss. By stimulating these receptors, tirzepatide enhances the body's natural ability to manage insulin and metabolism, leading to better appetite control, improved fat burning, and sustained weight reduction. This combined effect makes tirzepatide different from other weight loss treatments, offering a more comprehensive approach to long-term weight management.
Further Reading:
1. Farzam, Khashayar, and Preeti Patel. “Tirzepatide.” PubMed, StatPearls Publishing, 2022. www.ncbi.nlm.nih.gov/books/NBK585056/.
2. Heise, Tim, et al. “Tirzepatide Reduces Appetite, Energy Intake, and Fat Mass in People with Type 2 Diabetes.” Diabetes Care, 1 Mar. 2023. https://doi.org/10.2337/dc22-1710.
3. “Tirzepatide Has Unique Activity to Stimulate Insulin Secretion.” Duke Health, 2 June 2023. corporate.dukehealth.org/news/tirzepatide-has-unique-activity-stimulate-insulin-secretion. Accessed 18 Mar. 2024.
4. “Tirzepatide (Weight Loss) Subcutaneous: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD.” www.webmd.com/drugs/2/drug-187793/tirzepatide-weight-loss-subcutaneous/details. Accessed 18 Mar. 2024.